“In all genuine conviction of sin, the great burden of pollution and guilt is felt to consist not in what we have done, but in what we are–our permanent moral condition rather than our actual transgressions [i.e. our estate of sin and misery]. The great cry is to be forgiven and delivered from “the wicked heart of unbelief,” “deadness to divine things, alienated from God as a permanent habit of soul.” “O wretched man that I am! who shall deliver me from the body of this death?” Rom. vii. 24; Ps. li. 5, 6. It hence necessarily follows that original sin, as well as actual transgressions, deserves the curse of the law. Everything condemned by the law is under its curse” (A.A. Hodge, The Confession of Faith, 116-117).

Also see Question XXVIII from The Shorter Catechism:

Question: Wherein consists the sinfulness of the estate whereinto man fell? 

Answer: The sinfulness of that estate whereinto man fell, consists in the guilt of Adam’s first sin, the want of original righteousness, and the corruption of his whole nature, which is commonly called original sin, together with all actual transgressions which proceed from it.